Reduction in Choline Acetyltransferase Immunoreactivity but not Muscarinic-M2 Receptor Immunoreactivity in the Brainstem of SIDS Infants
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چکیده
منابع مشابه
Choline acetyltransferase (ChAT) immunoreactivity in paraffin sections of normal and diseased intestines.
There is increasing interest in localizing nerves in the intestine, especially specific populations of nerves. At present, the usual histochemical marker for cholinergic nerves in tissue sections is acetylcholinesterase activity. However, such techniques are applicable only to frozen sections and have uncertain specificity. Choline acetyltransferase (ChAT) is also present in cholinergic nerves,...
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We have studied the distribution of neurokinin A-like immunoreactive cell bodies and fibers in the cat brainstem. The densest clusters of perikarya containing the peptide were observed in the periaqueductal gray, inferior colliculus, postpyramidal nucleus of the raphe, medial nucleus of the solitary tract and in the lateral reticular nucleus. By contrast, the interpeduncular nucleus, magnocellu...
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Transcripts of the choline acetyltransferase (ChAT) gene reveal a number of different splice variants including ChAT of a peripheral type (pChAT). Immunohistochemical staining of the brain using an antibody against pChAT clearly revealed peripheral cholinergic neurons, but failed to detect cholinergic neurons in the central nervous system. In rodents, pChAT-immunoreactivity has been detected in...
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چکیده ندارد.
15 صفحه اولM2, M3 and M4, but not M1, muscarinic receptor subtypes are present in rat spinal cord.
Muscarinic receptors in the spinal cord have been shown to mediate antinociception and alter blood pressure. Currently, there is much interest in identifying which muscarinic receptor subtypes regulate these functions. Toward that end, this study aimed to identify and localize the muscarinic receptor subtypes present in spinal cord using in vitro receptor autoradiography with [3H]-pirenzepine a...
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ژورنال
عنوان ژورنال: Journal of Neuropathology and Experimental Neurology
سال: 1999
ISSN: 0022-3069
DOI: 10.1097/00005072-199903000-00005